About Meshima Ingredients
Meshima is a potent extract derived from Sanghwang (Phellinus linteus) — a rare medicinal mushroom highly valued in traditional Korean medicine for its immune-enhancing and anti-tumor properties. Rich in natural polysaccharides like α-(1,6)-heteroglycan and galactomannoglucan, Sanghwang supports the body’s ability to defend itself at the cellular level. This is what makes Meshima a trusted ingredient in advanced functional health products.
For Immune Strength and Better Health
The World of Medicinal Mushrooms
Looking for a natural way to boost your immune system?
Nature has long held the answer.
Medicinal mushrooms are packed with powerful compounds that help your body defend, recover, and thrive—
a fact recognized by over 75% of the world’s population, who continue to rely on natural solutions for everyday wellness.
As chronic illness becomes more common and concerns over synthetic drugs increase, people are actively seeking safer, gentler, and more sustainable ways to stay healthy.
This is where medicinal mushrooms stand out—with a balance of tradition and modern science.
A Powerful Immune Modulator from Nature
Medicinal Mushrooms
Unlike chemical treatments that can weaken the body, {{medicinal}} mushrooms work in harmony with your immune system. Through hot water extraction, they release vital compounds like polysaccharides and triterpenoids—
recognized for their immune-boosting and anti-tumor properties. In particular, mushrooms from the Basidiomycota family have been shown to support cellular defense without harming healthy cells.
Key Types of Medicinal Mushrooms and Their Benefits
Lion’s Mane Mushroom
Known for its cognitive benefits, Lion’s Mane contains two key compounds—erinacines and hericenones—that support the production of Nerve Growth Factor (NGF).
These natural substances help protect brain cells, enhance memory, and may play a role in preventing age-related cognitive decline.
Recent studies have also explored its potential in preventing Alzheimer’s disease and protecting the stomach lining, making it a promising ingredient for both brain and gut health.
Sanghwang Mushroom
Widely regarded as one of the most powerful immune-enhancing and anti-cancer medicinal mushrooms, Sanghwang (Phellinus linteus) is rich in bioactive polysaccharides.
Its mycelial extract, known as Meshima, contains high levels of beta-glucans and large-molecule compounds such as α-(1,6)-heteroglycan and galactomannoglucan—recognized for their potent immune-modulating properties.
Reishi
Mushroom
Revered as the “Mushroom of Immortality” in Eastern medicine, Reishi is celebrated for its immune-balancing and antioxidant properties. It contains triterpenoids and beta-glucans, both of which are well-researched for their health-supporting effects.
Traditionally used to protect the liver, regulate blood pressure, and reduce stress, Reishi continues to be studied for its role in immune support and as a complementary agent in cancer therapy.
Chaga
Mushroom
Chaga thrives in extreme climates and is known for its resilience and exceptional antioxidant content.
It is naturally rich in betulinic acid and polyphenols, which contribute to its free radical-fighting potential.
Traditionally used in Russia and Eastern Europe to support immunity and cancer prevention, Chaga is now being studied for its effects on blood sugar balance and inflammation.
Why Sanghwang Mycelial Extract
Is Redefining Immune Support
Among the many medicinal mushrooms, Sanghwang (Phellinus linteus) stands out for one reason: potency.
While all mushrooms contain beneficial compounds, what truly determines their efficacy is the concentration of active ingredients.
Sanghwang mycelial extract delivers highly concentrated polysaccharides known for their unmatched immune-modulating and anti-cancer potential.
Clinically Researched, Naturally Powerful
Recent studies reveal that extracts from Sanghwang can activate immune cells, suppress inflammation, and disrupt cancer cell proliferation.
Even more promising, it shows synergistic potential when used alongside chemotherapy—enhancing efficacy without harming healthy tissue.
More Than Reishi or Chaga —
A New Benchmark in Functional Mushrooms
Reishi and Chaga remain popular for immune and antioxidant benefits, but Sanghwang extract consistently outperforms them
when it comes to immune cell activation and tumor suppression—making it the top contender in functional formulations for immunity.
The Power of Sanghwang Mushroom Extract
From Supplement to Therapeutic Ally
This extract doesn’t just support the immune system—it helps optimize it.
By working in harmony with the body’s natural defenses, Sanghwang extract can help enhance cancer treatment, reduce inflammation, and restore balance in immune-compromised conditions.
Sanghwang Mycelium
A Breakthrough Ingredient for
Next-Generation Immune Therapies
Recent research suggests that when used alongside chemotherapy, they may help maximize the effectiveness of cancer treatment—without the toxicity typically associated with synthetic drugs.
The medical field is increasingly exploring medicinal mushrooms as complementary options in immune-based therapies. And among them, Sanghwang stands out as a natural candidate backed by both traditional use and emerging clinical interest.
For consumers and professionals alike, choosing a medicinal mushroom isn’t just about what it looks like—it’s about what’s inside. Scientifically validated ingredients with high concentrations of active compounds offer the most real-world benefits.
Sanghwang mycelium is more than a supplement — it’s a powerful bioactive ingredient with the potential to enhance immune health and support integrative cancer care.
With ongoing clinical research, Sanghwang mycelium is well on its way to becoming a core pillar in the future of immune-based healthcare.
Mesima, the Most Advanced Immune Activator from Sanghwang Mycelium
Unlike standard polysaccharides found in many mushrooms, Mesima is composed of rare protein-bound polysaccharides — complex proteoglycans that deliver exceptional immune-activating and anti-cancer effects.
While Reishi, Chaga, and Lion’s Mane offer impressive health benefits, Mesima stands out for its unparalleled ability to stimulate immune cells and suppress tumor activity — making it a prime candidate in the development of next-generation immunotherapeutics.
More Than Appearance :
The Science Inside Matters
Today’s medical science doesn’t judge mushrooms by appearance.
The real value lies in their active compound profile and physiological impact.
Mesima is a clear standout, forming complex 3D proteoglycan structures that interact directly with immune cells for maximum effect.
The Discovery of a New Bioactive Giant:
153kDa Acidic Proteoglycan
Instrumental analysis of Mesima has led to the identification of a new bioactive component:
a 153 kilodalton (kDa) acidic proteoglycan composed of specific immune-stimulating units — a potential breakthrough in the search for safer, more effective cancer therapies.
The Architecture of Immunity:
Mesima’s Unique Structure
Mesima’s cancer-fighting power doesn’t come from a single sugar molecule — it’s the result of a highly organized 3D matrix made of galactomannoglucans and other saccharide-protein units.
These structures don’t just exist—they actively stimulate the immune system to identify and eliminate abnormal cells.
When these polysaccharides exist in simple, unbound form, they show little to no activity. It’s only when they assemble into complex networks that their therapeutic potential is fully activated.
Inside Mesima: Structure, Sugar Composition, and Molecular Power
The true power of Mesima lies not just in its ingredients—but in how they’re built.
One of its core components, galactomannoglucan, forms complex 3D structures when dozens of repeating sugar units interlink. This spatial arrangement is the key to Mesima’s anti-cancer bioactivity.
What Makes Mesima Unique:
A True Proteoglycan Complex
Unlike standard polysaccharides, Mesima’s structure includes proteins bonded to sugars, forming a proteoglycan complex.
This allows for more targeted immune signaling and enhanced cellular recognition.
The Mechanism: How Mesima Works Against Cancer
Mesima activates immune function not by attacking cells directly, but by stimulating key players in the immune system to do the work.
Activating the Body’s Defense Cells
Its proteoglycans bind to immune cell receptors—like Toll-like receptors—triggering a cascade of immune responses.
Key immune cells such as macrophages, T-cells, and NK cells are mobilized —enhancing the body’s ability to recognize and destroy abnormal cells.
Antioxidant and Anti-inflammatory Effects
Mesima also reduces oxidative stress by suppressing reactive oxygen species (ROS), protecting healthy cells from damage while lowering systemic inflammation.
This dual action makes it a promising candidate for preventing tumor growth and metastasis.
Especially noteworthy is its effect on NK (Natural Killer) cells,
which are responsible for directly attacking tumor cells.
Mesima has been shown to enhance NK cell cytotoxicity, improving the body’s front-line defense.
A Natural Synergist with Chemotherapy
Unlike many supplements, Mesima is not just complementary — it’s cooperative. Studies indicate that when combined with conventional chemotherapy,
Mesima may help amplify cancer cell death while reducing side effects.
This positions Mesima as a valuable addition to integrative cancer care — bridging natural immunity with modern oncology.
Extracted from the mycelium of Sanghwang mushroom,
The Polysaccharide Profile of Mesima
T-value
Molar Ratio (%)
Arabinose
1
7.0%
Xylose
1.135
3.7%
Mannose
1.412
44.2%
Galactose
1.39
24.1%
Glucose
1.566
21.1%
The Polysaccharide Profile of
Mesima
Extracted from the mycelium of Sanghwang mushroom,
{{Mesima}} features a unique polysaccharide profile rich in mannose and arabinose — two sugar units that are not only rare in typical mushroom extracts but also closely linked to immune modulation.
Mannose plays a key role in cellular communication and immune recognition, while arabinose—commonly found in plant cell walls—displays potent biological activity when structured into specific 3D forms.
Extracted from the mycelium of Sanghwang mushroom,
Amino Acid Content in Mesima
Amino Acids
Content (nmol/mg)
Asp
1
Thr
1.135
Ser
1.412
Glu
1.39
Gly
1.566
Gly
1.566
Gly
1.566
Gly
1.566
Gly
1.566
Gly
1.566
Contains
Essential Amino Acids
What sets {{Mesima}} apart is not just its sugars, but its synergy of protein and polysaccharide.
Its proteoglycan structure includes a spectrum of essential amino acids—critical for cellular metabolism and immune system function.
This makes {{Mesima}} not just an immune booster,
but a comprehensive bioactive compound that supports both defense and recovery at the cellular level.